Description

6-((tert-Butyldimethylsilyl)Oxy)-9H-Pyrido[3,4-B]Indole is a sophisticated, high-purity chemical intermediate featuring a protected hydroxyl group on a complex heterocyclic core. This compound matters for its critical role as a key building block in advanced pharmaceutical research and development, enabling the synthesis of complex molecules with precision. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries working on novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its unique heterocyclic structure.
• Fine Chemical Synthesis: Acts as a specialized building block for creating complex organic molecules in custom synthesis and contract manufacturing.
• Academic & Institutional R&D: Employed in university and research institute laboratories for methodological studies and the exploration of new chemical entities.
• Process Chemistry Development: Utilized for scaling up synthetic routes from laboratory to pilot plant scale, where the silyl protecting group offers strategic advantages.

Basic Information

Product Name	6-((tert-Butyldimethylsilyl)Oxy)-9H-Pyrido[3,4-B]Indole
CAS No.	1800542-62-4
Molecular Formula	C17H24N2OSi
Molecular Weight	300.48 g/mol
Synonyms	6-(tert-Butyldimethylsilyloxy)-9H-pyrido[3,4-b]indole; 6-OTBS-9H-Pyrido[3,4-b]indole; Norharman-6-ol TBDMS ether; 6-TBDMSoxy-β-carboline; 9H-Pyrido[3,4-b]indol-6-ol, 1-(1,1-dimethylethyl)-1,1-dimethylsilyl ether; TBDMS-protected 6-hydroxynorharman; 6-Hydroxy-β-carboline TBDMS ether
EINECS	Contact for details

Quality Control

Our 6-((tert-Butyldimethylsilyl)Oxy)-9H-Pyrido[3,4-B]Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed under an inert atmosphere to maximize stability, as the compound is light-sensitive.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.