Description

Borussertib is a potent and selective small molecule inhibitor targeting specific kinase pathways involved in cellular signaling. This compound is of significant interest for research and development in the life sciences sector, particularly for its potential in investigating disease mechanisms. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on oncology and related therapeutic areas. Borussertib CAS NO 1800070-77-2 represents a high-purity chemical tool for advancing preclinical studies.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the discovery and development of novel therapeutic agents.
• Biochemical Assay Development: Used as a precise inhibitor in in vitro enzymatic and cell-based assays to study kinase function and signaling cascades.
• Target Validation Studies: Employed in preclinical research to validate specific biological targets and understand their role in disease pathology.
• Academic & Institutional Research: Provides a reliable chemical probe for fundamental research in molecular biology, cancer biology, and signal transduction.
• High-Throughput Screening (HTS): Utilized in compound libraries for screening campaigns to identify and optimize lead compounds with similar mechanisms of action.
• Process Chemistry & Scale-Up: Acts as a critical intermediate for process chemists during the optimization and scale-up of synthetic routes for potential drug candidates.

Basic Information

Product Name	Borussertib
CAS No.	1800070-77-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	BORUSSERTIB; 1800070-77-2; UNII-1K2J8W8W3I; 1K2J8W8W3I; BDBM50391489; AKOS040759906; (S)-Borussertib; Borussertib (S-enantiomer); Borussertib free base
EINECS	Contact for details

Quality Control

Our Borussertib is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (typically 15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at lower temperatures (e.g., -20°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.