Description

(2-Bromo-4-Chloro-3-Fluorophenyl)Methanol is a halogenated benzyl alcohol derivative, a versatile and high-value building block in advanced organic synthesis. Its multi-halogenated aromatic structure makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the halogen pattern influences bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated and chlorinated components in electronic display and lighting materials, enhancing performance and durability.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce halogenated aromatic groups into polymer chains, modifying thermal and chemical resistance.
• Organic Ligand Synthesis: Utilized to create specialized ligands for catalysis and metal-organic frameworks (MOFs), leveraging the halogen substituents for fine-tuning coordination properties.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry and material science R&D for structure-activity relationship (SAR) studies and novel compound libraries.

Basic Information

Product Name	(2-Bromo-4-Chloro-3-Fluorophenyl)Methanol
CAS No.	1785320-57-1
Molecular Formula	C7H5BrClFO
Molecular Weight	239.47 g/mol
Synonyms	(2-Bromo-4-chloro-3-fluorophenyl)methanol; 2-Bromo-4-chloro-3-fluorobenzyl alcohol; α-(2-Bromo-4-chloro-3-fluorophenyl)methanol; Benzenemethanol, 2-bromo-4-chloro-3-fluoro-; 3-Fluoro-2-bromo-4-chlorobenzyl alcohol; 4-Chloro-2-bromo-3-fluorobenzyl alcohol; CAS 1785320-57-1
EINECS	Contact for details

Quality Control

Our (2-Bromo-4-Chloro-3-Fluorophenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and residual solvent analysis, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.