Description

(3,5-Difluoro-4-Methylphenyl)Methanol is a high-purity fluorinated aromatic alcohol building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and the reactive benzylic alcohol group, enabling precise molecular modifications. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially in kinase inhibitors and CNS-active molecules where fluorine substitution modulates bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in constructing advanced herbicides, fungicides, and pesticides, leveraging the fluorine atoms to enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, where fluorine improves thermal stability and optical properties.
• Polymer & Resin Modification: Incorporated as a monomer or cross-linking agent to introduce fluorine into polymer backbones, enhancing chemical resistance and surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and ether formations to introduce the difluoromethylphenyl moiety into more complex molecular architectures.
• Fluorinated Surfactant & Coating Precursor: Used to synthesize specialty surfactants and surface treatment agents that require low surface energy and high stability.

Basic Information

Item	Details
Product Name	(3,5-Difluoro-4-Methylphenyl)Methanol
CAS No.	1783540-14-6
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	4-(Hydroxymethyl)-2,6-difluorotoluene; (3,5-Difluoro-4-methylphenyl)methanol; 2,6-Difluoro-4-methylbenzyl alcohol; 4-Methyl-3,5-difluorobenzyl alcohol; α-Hydroxy-3,5-difluoro-4-methyltoluene; 3,5-Difluoro-4-methylbenzenemethanol; (3,5-Difluoro-p-tolyl)methanol
EINECS	Contact for details

Quality Control

Our (3,5-Difluoro-4-Methylphenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.