Description

1-(2-(Difluoromethyl)Phenyl)Ethanol is a versatile chiral building block and fluorinated intermediate of significant interest in advanced organic synthesis. Its value lies in the strategic incorporation of fluorine and a benzylic alcohol group, which are critical for modulating the physicochemical and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with enhanced metabolic stability, bioavailability, and binding selectivity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides where fluorine atoms improve lipophilicity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the development of fluorinated components for electronic display and lighting technologies due to its impact on molecular polarity and alignment.
• Chiral Ligand & Catalyst Preparation: Serves as a starting material for synthesizing enantiomerically pure ligands used in asymmetric catalysis.
• Advanced Polymer Modifiers: Incorporated into specialty polymers to impart unique surface properties, chemical resistance, and optical characteristics.
• Organic Synthesis Research: A valuable reagent for method development and exploring new fluorination and functionalization pathways in academic and industrial R&D settings.

Basic Information

Product Name	1-(2-(Difluoromethyl)Phenyl)Ethanol
CAS No.	1783382-76-2
Molecular Formula	C9H10F2O
Molecular Weight	172.17 g/mol
Synonyms	α-(2-(Difluoromethyl)phenyl)ethanol; 1-[2-(Difluoromethyl)phenyl]ethan-1-ol; (2-(Difluoromethyl)phenyl)methylcarbinol; 2-(Difluoromethyl)benzenemethanol, α-methyl-; 1-(2-(Difluoromethyl)phenyl)ethyl alcohol; rac-1-(2-(Difluoromethyl)phenyl)ethanol
EINECS	Contact for details

Quality Control

Our production of 1-(2-(Difluoromethyl)Phenyl)Ethanol adheres to a stringent quality management system to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against rigorous in-house specifications, which typically include chiral purity, chemical identity, and impurity profile analysis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.