Description

2,2-Difluoro-2-(4-(Trifluoromethyl)Phenyl)Ethanol is a high-value fluorinated aromatic building block characterized by its unique difluoroethanol and trifluoromethylphenyl functional groups. This compound is essential for introducing fluorine atoms into target molecules, a key strategy in modern pharmaceutical and agrochemical research to modulate bioavailability, metabolic stability, and lipophilicity. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of new drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorine substitution enhances biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated components for high-performance liquid crystal displays (LCDs).
• Organic Electronics: Employed in the development of novel materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Advanced Polymer Chemistry: Acts as a monomer or modifier to create fluorinated polymers with enhanced chemical resistance and thermal stability.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and constructing complex molecular architectures in academic and industrial labs.

Basic Information

Product Name	2,2-Difluoro-2-(4-(Trifluoromethyl)Phenyl)Ethanol
CAS No.	1781189-72-7
Molecular Formula	C9H7F5O
Molecular Weight	226.14 g/mol
Synonyms	2,2-Difluoro-2-[4-(trifluoromethyl)phenyl]ethanol; 1-[4-(Trifluoromethyl)phenyl]-2,2-difluoroethanol; α,α-Difluoro-4-(trifluoromethyl)benzeneethanol; 4-(Trifluoromethyl)benzene-α,α-difluoroethanol; 2,2-Difluoro-1-(4-trifluoromethylphenyl)ethanol; 2-(4-Trifluoromethylphenyl)-2,2-difluoroethanol; (4-Trifluoromethylphenyl)difluoroethanol
EINECS	Contact for details

Quality Control

Every batch of 2,2-Difluoro-2-(4-(Trifluoromethyl)Phenyl)Ethanol is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.