Description

(3-Chloro-6-Fluoro-2-Methoxyphenyl)Methanol CAS NO 1780183-58-5 is a high-purity fluorinated and chlorinated benzyl alcohol derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique substitution pattern, which provides a versatile scaffold for constructing complex molecules in medicinal chemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for synthesizing novel active ingredients targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging its halogenated aromatic structure.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Chemical Biology Probes: Utilized as a precursor for creating fluorescent tags or molecular probes for biochemical assays.
• Organic Synthesis: Versatile starting material for further functionalization, including oxidation to aldehydes or esterification, in complex multi-step syntheses.

Basic Information

Product Name	(3-Chloro-6-Fluoro-2-Methoxyphenyl)Methanol
CAS No.	1780183-58-5
Molecular Formula	C8H8ClFO2
Molecular Weight	190.60 g/mol
Synonyms	2-Methoxy-6-fluoro-3-chlorobenzyl alcohol; (6-Fluoro-2-methoxy-3-chlorophenyl)methanol; 3-Chloro-6-fluoro-2-methoxybenzenemethanol; 1-(3-Chloro-6-fluoro-2-methoxyphenyl)methanol; α-Hydroxymethyl-3-chloro-6-fluoro-2-methoxybenzene
EINECS	Contact for details

Quality Control

Our (3-Chloro-6-Fluoro-2-Methoxyphenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storage under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.