Description

n-((3R,4R)-4-Fluoro-1-(6-((3-Methoxy-1-Methyl-1H-Pyrazol-4-Yl)Amino)-9-Methyl-9H-Purin-2-Yl)Pyrrolidin-3-Yl)Acrylamide is a high-purity, advanced pharmaceutical intermediate designed for precision synthesis. This compound is critical for research and development in targeted therapeutic areas, offering a key building block for novel drug candidates. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers specializing in oncology and other specialized medicinal chemistry applications.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel kinase inhibitors and other targeted small-molecule therapeutics.
• Oncology Research: Used in the discovery and preclinical study of potential anti-cancer agents due to its specific purine-based structure.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for clinical trial material production.
• Biochemical Research: May be used as a tool compound to study specific enzymatic pathways and protein interactions.
• Custom Synthesis: A starting material for the contract manufacturing of specialized APIs (Active Pharmaceutical Ingredients) under cGMP conditions.

Basic Information

Product Name	n-((3R,4R)-4-Fluoro-1-(6-((3-Methoxy-1-Methyl-1H-Pyrazol-4-Yl)Amino)-9-Methyl-9H-Purin-2-Yl)Pyrrolidin-3-Yl)Acrylamide
CAS No.	1776112-90-3
Molecular Formula	C18H22FN9O2
Molecular Weight	415.43 g/mol
Synonyms	(3R,4R)-4-Fluoro-1-[6-[(3-methoxy-1-methylpyrazol-4-yl)amino]-9-methylpurin-2-yl]pyrrolidine-3-carboxamide; 4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)-N-[(3R,4R)-pyrrolidin-3-yl]acrylamide; UNII-7J4I9F6P4F; 1776112-90-3; Acrylamide, N-[(3R,4R)-4-fluoro-1-[6-[(3-methoxy-1-methyl-1H-pyrazol-4-yl)amino]-9-methyl-9H-purin-2-yl]-3-pyrrolidinyl]-
EINECS	Contact for details

Quality Control

Our production of n-((3R,4R)-4-Fluoro-1-(6-((3-Methoxy-1-Methyl-1H-Pyrazol-4-Yl)Amino)-9-Methyl-9H-Purin-2-Yl)Pyrrolidin-3-Yl)Acrylamide adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.