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(S)-4,5-Dichloro-n-((2-Oxo-3-(4-(3-Oxomorpholino)Phenyl)Oxazolidin-5-Yl)Methyl)Thiophene-2-Carboxamide CAS NO 1770812-37-7


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CAS No.:1770812-37-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(S)-4,5-Dichloro-n-((2-Oxo-3-(4-(3-Oxomorpholino)Phenyl)Oxazolidin-5-Yl)Methyl)Thiophene-2-Carboxamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, particularly in the creation of new therapeutic agents targeting complex diseases. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of next-generation oxazolidinone-based drugs.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of novel oxazolidinone-class antibiotics and other therapeutic agents.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
  • API Development: Serves as a critical precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
  • Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production.
  • Biochemical Research: Investigated for its biological activity and potential as a probe in biochemical assays.
  • Process Chemistry: Used in the development and scale-up of efficient synthetic routes for pharmaceutical production.

Basic Information

Product Name (S)-4,5-Dichloro-n-((2-Oxo-3-(4-(3-Oxomorpholino)Phenyl)Oxazolidin-5-Yl)Methyl)Thiophene-2-Carboxamide
CAS No. 1770812-37-7
Molecular Formula C20H17Cl2N3O5S
Molecular Weight 482.34 g/mol
Synonyms (S)-4,5-Dichloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)thiophene-2-carboxamide; 4,5-Dichloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide; UNII-6Q9K3VJ66P; 6Q9K3VJ66P; Thiophene-2-carboxamide, 4,5-dichloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-; (S)-Oxazolidinone-thiophene carboxamide derivative
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Quality Control

Our production of (S)-4,5-Dichloro-n-((2-Oxo-3-(4-(3-Oxomorpholino)Phenyl)Oxazolidin-5-Yl)Methyl)Thiophene-2-Carboxamide adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral HPLC for enantiomeric excess, and NMR/IR for structural confirmation, to ensure high chemical and isomeric purity suitable for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to maintain long-term stability and purity.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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