Description

3,4-Dichloro-5-(Trifluoromethoxy)Benzoyl Chloride is a high-purity, multi-functional aromatic acid chloride intermediate. This compound is valued for its unique trifluoromethoxy and benzoyl chloride groups, which enable its use as a critical building block in advanced synthetic chemistry. It is primarily required by R&D and production chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring the 3,4-dichloro-5-(trifluoromethoxy)phenyl moiety.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials due to its aromatic and halogenated structure.
• Custom Synthesis & Contract Manufacturing: An essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3,4-Dichloro-5-(Trifluoromethoxy)Benzoyl Chloride
CAS No.	1706458-00-5
Molecular Formula	C8H2Cl3F3O2
Molecular Weight	303.46 g/mol
Synonyms	3,4-Dichloro-5-(trifluoromethoxy)benzoyl chloride; 3,4-Dichloro-alpha,alpha,α-trifluoro-5-methoxybenzoyl chloride; 5-(Trifluoromethoxy)isophthaloyl chloride, 3,4-dichloro-; Benzoyl chloride, 3,4-dichloro-5-(trifluoromethoxy)-; 3,4-Dichloro-5-(trifluoromethoxy)benzoic acid chloride
EINECS	Contact for details

Quality Control

Our 3,4-Dichloro-5-(Trifluoromethoxy)Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.