Description

4-Bromo-3-Chloro-2-Fluorobenzyl Alcohol is a high-purity, multi-halogenated benzyl alcohol derivative serving as a critical building block in advanced organic synthesis. This compound matters for its precise molecular architecture, enabling the introduction of a functionalized benzyl moiety with distinct halogen substituents that direct subsequent chemical transformations. It is primarily needed by pharmaceutical and agrochemical R&D teams for developing new active ingredients, as well as by specialty chemical manufacturers producing complex intermediates for electronics and material science applications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the halogen pattern contributes to biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated and halogenated components in electronic display materials, enhancing their dielectric and optical properties.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored thermal and chemical resistance.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and exploring new reaction pathways in halogen chemistry.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses producing bespoke intermediates for client-specific projects.

Basic Information

Product Name	4-Bromo-3-Chloro-2-Fluorobenzyl Alcohol
CAS No.	1702154-18-4
Molecular Formula	C7H5BrClFO
Molecular Weight	239.47 g/mol
Synonyms	(4-Bromo-3-chloro-2-fluorophenyl)methanol; 2-Fluoro-4-bromo-3-chlorobenzyl alcohol; 1-(Bromomethyl)-2-chloro-3-fluoro-4-bromobenzene (deprecated); Benzenemethanol, 4-bromo-3-chloro-2-fluoro-; 4-Bromo-3-chloro-2-fluoro-benzenemethanol; BCFB Alcohol; Halogenated Benzyl Alcohol Derivative
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Chloro-2-Fluorobenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We adhere to cGMP principles where applicable, ensuring reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.