Description

Diazenecarboximidamide, n-(Hydroxymethyl)-n-β-D-Ribofuranosyl- is a specialized nucleoside analog of significant interest in advanced pharmaceutical research and development. Its unique structure, featuring a diazene-modified base linked to a ribofuranosyl sugar, makes it a valuable building block for probing biological mechanisms and developing novel therapeutic agents. This high-purity compound is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of nucleoside-based drug candidates, antiviral research, and biochemical studies. We supply this material with a focus on batch-to-batch consistency and reliable documentation to support critical R&D workflows.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways and nucleic acid biochemistry.
• Probe Development: Employed in the design and synthesis of molecular probes for studying gene expression, DNA/RNA interactions, and cellular processes.
• Antiviral Research: Investigated for its potential activity or as a scaffold for modifying the pharmacokinetic properties of therapeutic nucleosides.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental chemical and biological research projects.
• Process Chemistry: Used in route scouting and optimization for the scalable synthesis of complex nucleoside derivatives.

Basic Information

Product Name	Diazenecarboximidamide, n-(Hydroxymethyl)-n-β-D-Ribofuranosyl-
CAS No.	1698011-17-4
Molecular Formula	C7H14N4O5
Molecular Weight	234.21 g/mol
Synonyms	N-(Hydroxymethyl)-N-β-D-ribofuranosyldiazenecarboximidamide; 1-(β-D-Ribofuranosyl)-2-(hydroxymethyl)diazene-1-carboximidamide; Modified Nucleoside Derivative; Ribofuranosyl Diazene Carboximidamide; Research Grade Nucleoside Analog; CAS 1698011-17-4
EINECS	Contact for details

Quality Control

Our Diazenecarboximidamide, n-(Hydroxymethyl)-n-β-D-Ribofuranosyl- is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.