Description

n-Methyl-n-((3R,4R)-4-Methylpiperidin-3-Yl)-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in targeted therapeutic agents. It is essential for pharmaceutical companies and contract research organizations (CROs) focused on developing novel small-molecule drugs, especially in oncology and other precision medicine fields.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs).
• Oncology Drug Discovery: Used in R&D for targeted cancer therapies, particularly kinase inhibitors.
• Medicinal Chemistry Research: A key substrate for structure-activity relationship (SAR) studies and lead optimization.
• Preclinical Development: Employed in the production of compounds for pharmacological and toxicological evaluation.
• Process Chemistry: Utilized in route scouting and scale-up studies for efficient API manufacturing.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	n-Methyl-n-((3R,4R)-4-Methylpiperidin-3-Yl)-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine Dihydrochloride
CAS No.	1655430-59-3
Molecular Formula	C13H22Cl2N6
Molecular Weight	333.26 g/mol
Synonyms	4-Amino-7H-pyrrolo[2,3-d]pyrimidine, N-methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-, dihydrochloride; (3R,4R)-N-Methyl-N-(4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine dihydrochloride; CAS 1655430-59-3; 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, N-methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-, dihydrochloride; (R,R)-Isomer of N-Methyl-N-(4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine dihydrochloride
EINECS	Contact for details

Quality Control

Our n-Methyl-n-((3R,4R)-4-Methylpiperidin-3-Yl)-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% de
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.