Description

5-Benzylaminocarbony-2'-o-Methyl-Uridine is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical and biochemical research. This compound serves as a critical building block for the synthesis of oligonucleotides with tailored properties, such as enhanced stability and specific binding affinity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic probes, and tools for molecular biology.

Application

• Oligonucleotide Synthesis: A key monomer for the solid-phase synthesis of modified antisense oligonucleotides (ASOs) and small interfering RNAs (siRNAs).
• Pharmaceutical Research: Used as an intermediate in the development of nucleoside-based prodrugs and antiviral/anticancer agents.
• Biochemical Probes: Incorporated into nucleic acid probes to study RNA structure, function, and protein-RNA interactions.
• Diagnostic Development: Serves as a component in the design of sensitive molecular diagnostic assays and detection systems.
• Academic Research: Employed in university and institutional labs for fundamental studies on nucleic acid chemistry and modification.

Basic Information

Product Name	5-Benzylaminocarbony-2'-o-Methyl-Uridine
CAS No.	1648558-95-5
Molecular Formula	C18H21N3O7
Molecular Weight	391.38 g/mol
Synonyms	2'-O-Methyl-5-(benzylaminocarbonyl)uridine; 5-(Benzylcarbamoyl)-2'-O-methyluridine; 2'-O-Methyl-5-carbamoyluridine Benzyl Ester; 5-(N-Benzylcarbamoyl)-2'-O-methyluridine; BzUrd(2'OMe); Modified Nucleoside Monomer; CAS 1648558-95-5
EINECS	Contact for details

Quality Control

Our 5-Benzylaminocarbony-2'-o-Methyl-Uridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.