Description

Ethanone, 2-(3,5-Dimethyl-1H-1,2,4-Triazol-1-Yl)-1-[(2R)-2-Methyl-4-[2-(Trifluoromethyl)-4-[2-(Trifluoromethyl)-5-Pyrimidinyl]-5-Thiazolyl]-1-Piperazinyl]- is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and antiviral research.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Serves as a critical intermediate in the scale-up and commercial manufacturing of complex APIs.
• Biochemical Research: Employed in the study of enzyme inhibition and receptor binding assays due to its specific molecular architecture.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Ethanone, 2-(3,5-Dimethyl-1H-1,2,4-Triazol-1-Yl)-1-[(2R)-2-Methyl-4-[2-(Trifluoromethyl)-4-[2-(Trifluoromethyl)-5-Pyrimidinyl]-5-Thiazolyl]-1-Piperazinyl]-
CAS No.	1646267-59-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2-(3,5-Dimethyl-1H-1,2,4-triazol-1-yl)-1-[(2R)-2-methyl-4-[2-(trifluoromethyl)-4-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-thiazol-5-yl]piperazin-1-yl]ethanone; (2R)-2-Methyl-4-[2-(trifluoromethyl)-4-[2-(trifluoromethyl)-5-pyrimidinyl]-5-thiazolyl]-1-piperazine Ethanone Derivative; CAS 1646267-59-5; Advanced Triazole-Thiazole-Piperazine Intermediate.
EINECS	Contact for details

Quality Control

Our Ethanone, 2-(3,5-Dimethyl-1H-1,2,4-Triazol-1-Yl)-1-[(2R)-2-Methyl-4-[2-(Trifluoromethyl)-4-[2-(Trifluoromethyl)-5-Pyrimidinyl]-5-Thiazolyl]-1-Piperazinyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.