Description

Glumetinib is a potent and selective small-molecule inhibitor targeting specific tyrosine kinase receptors. This compound is of significant interest in pharmaceutical research and development for its targeted therapeutic potential. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology drug discovery and preclinical studies.

Application

• Pharmaceutical Research & Development: Serves as a key active pharmaceutical ingredient (API) intermediate or reference standard in the development of novel targeted cancer therapies.
• Biochemical Research: Used as a selective inhibitor in enzymatic and cellular assays to study specific kinase signaling pathways and their role in disease mechanisms.
• Preclinical Studies: Employed in in vitro and in vivo models to evaluate efficacy, pharmacokinetics, and safety profiles of potential drug candidates.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	Glumetinib
CAS No.	1642581-63-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Glumetinib; Gumarontinib; HS-10342; Gumarontinib (HS-10342); (S)-N-(5-((1-Acryloylpyrrolidin-2-yl)methoxy)-7-((1-methyl-1H-pyrazol-4-yl)amino)pyrazolo[1,5-a]pyrimidin-3-yl)-N-methylpropionamide; HS10342; Gumarontinib; Gumarontinib (HS-10342)
EINECS	Contact for details

Quality Control

Our Glumetinib is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.