Description

(R)-Nedisertib CAS NO 1637542-32-5 is a high-purity, enantiomerically pure small molecule pharmaceutical intermediate and research chemical. This compound is of significant value for its role as a key chiral building block in advanced pharmaceutical synthesis and life science research. It is primarily needed by R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and pharmaceutical companies engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Biochemical Research: Used as a reference standard and tool compound in pharmacological and metabolic studies.
• Process Chemistry Development: Employed in route scouting and optimization for scalable, enantioselective manufacturing processes.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry projects and asymmetric synthesis methodology development.
• Quality Control Standard: Acts as an analytical standard for method development and validation in quality control laboratories.

Basic Information

Item	Details
Product Name	(R)-Nedisertib
CAS No.	1637542-32-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(R)-Nedisertib; (R)-Enantiomer of Nedisertib; M9831 (R-form); (R)-M9831; (R)-VX-984; (R)-4-((2-(4-(4-(((R)-1-(2-Chloro-6-fluorophenyl)ethyl)amino)-5-fluoro-2-oxopyridin-1(2H)-yl)piperidin-1-yl)-2-oxoethyl)amino)-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide; (R)-VX-984 Nedisertib
EINECS	Contact for details

Quality Control

Our (R)-Nedisertib is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high enantiomeric purity and chemical identity, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles are available upon request to support your regulatory and research documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment and handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.