Description

Ly2857785 is a potent and selective small molecule inhibitor targeting specific kinase pathways involved in cellular signaling. This high-purity compound is critical for advancing research in oncology and related life science fields. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and CROs for target validation, biochemical assays, and preclinical studies.

Application

• Biochemical and Cellular Research: Used as a selective tool compound to study specific kinase inhibition and downstream signaling pathways in vitro.
• Oncology Drug Discovery: Serves as a key reference standard and pharmacologically active probe in the development of novel anti-cancer therapeutics.
• Mechanism of Action (MoA) Studies: Employed to elucidate the role of specific kinase targets in disease models and normal physiology.
• High-Throughput Screening (HTS): Utilized as a control or validation compound in screening campaigns to identify new drug candidates.
• Preclinical Development: Supports pharmacokinetic (PK), pharmacodynamic (PD), and toxicology studies in animal models.

Basic Information

Product Name	Ly2857785
CAS No.	1619903-54-6
Molecular Formula	C₂₀H₂₀N₆O₂
Molecular Weight	376.42 g/mol
Synonyms	LY2857785; 4-[4-[[4-(3-Aminophenyl)-2-pyrimidinyl]amino]phenyl]-N-(4-methyl-3-pentenyl)-1-piperazinecarboxamide; 4-[4-({4-[3-Aminophenyl]pyrimidin-2-yl}amino)phenyl]-N-(4-methylpent-3-en-1-yl)piperazine-1-carboxamide; 4-(4-((4-(3-Aminophenyl)pyrimidin-2-yl)amino)phenyl)-N-(4-methylpent-3-en-1-yl)piperazine-1-carboxamide
EINECS	Contact for details

Quality Control

Our Ly2857785 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under inert atmosphere for long-term stability. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.