Description

(3-Chloro-2-Fluoro-4-Methoxyphenyl)Methanol is a high-purity fluorinated aromatic alcohol building block, essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the fluorine and chlorine substituents for enhanced bioactivity.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens used in advanced display technologies.
• Organic Electronic Materials: A starting material for synthesizing functionalized aromatic compounds used in OLEDs and organic semiconductors.
• Cross-Coupling Reactions: The benzylic alcohol group can be functionalized or used to prepare ligands for catalytic systems.
• Protecting Group Chemistry: The alcohol functionality can be protected or further derivatized in multi-step synthetic sequences.

Basic Information

Product Name	(3-Chloro-2-Fluoro-4-Methoxyphenyl)Methanol
CAS No.	1616601-81-0
Molecular Formula	C8H8ClFO2
Molecular Weight	190.60 g/mol
Synonyms	(3-Chloro-2-fluoro-4-methoxyphenyl)methanol; 2-Fluoro-3-chloro-4-methoxybenzyl alcohol; 3-Chloro-2-fluoro-4-methoxybenzenemethanol; 1-(3-Chloro-2-fluoro-4-methoxyphenyl)methanol; 4-Methoxy-3-chloro-2-fluorobenzyl alcohol; Benzenemethanol, 3-chloro-2-fluoro-4-methoxy-; CAS 1616601-81-0
EINECS	Contact for details

Quality Control

Every batch of (3-Chloro-2-Fluoro-4-Methoxyphenyl)Methanol is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, GC, NMR, and MS analysis, to ensure compliance with exacting industry standards and customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.