Description

N1-Benzyl Pseudouridine is a chemically modified nucleoside derivative, specifically a benzylated analog of pseudouridine. This compound is of significant value in the field of nucleic acid chemistry and therapeutic development due to its role in enhancing the stability and translational efficiency of synthetic mRNA. It is primarily sought after by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for advanced applications in mRNA vaccine and therapeutic production.

Application

• mRNA Vaccine & Therapeutic Production: A critical raw material for synthesizing modified mRNA to improve stability and reduce immunogenicity.
• Nucleic Acid Research: Used in biochemical studies to investigate the structure, function, and metabolism of RNA.
• Antiviral Drug Development: Serves as a building block in the synthesis of nucleoside analogs with potential antiviral activity.
• Bioconjugation & Probe Synthesis: Utilized for labeling and modifying oligonucleotides for diagnostic and research applications.
• Synthetic Biology: Incorporated into engineered RNA molecules to create novel functionalities and enhance performance.

Basic Information

Product Name	N1-Benzyl Pseudouridine
CAS No.	1613530-22-5
Molecular Formula	C₁₆H₁₈N₂O₆
Molecular Weight	334.32 g/mol
Synonyms	1-Benzylpseudouridine; ψ-Bzl; N1-Bzl-ψ; 1-Benzyl-5-ribosyluracil; Pseudouridine, 1-benzyl-; 5-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-benzylpyrimidine-2,4-dione
EINECS	Contact for details

Quality Control

Our N1-Benzyl Pseudouridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) documenting purity, related substances, and residual solvents are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.