Description

Teixobactin CAS NO 1613225-53-8 is a novel, first-in-class depsipeptide antibiotic with a unique mechanism of action, targeting lipid II in bacterial cell wall synthesis. This compound is of critical importance due to its potent activity against a broad spectrum of Gram-positive pathogens, including drug-resistant strains like MRSA and VRE, with no observed resistance development in initial studies. It is essential for pharmaceutical R&D teams, microbiologists, and clinical researchers focused on developing next-generation antimicrobial therapies to combat the global antibiotic resistance crisis.

Application

• Antibacterial Drug Discovery & Development: A key lead compound for research into novel classes of antibiotics targeting multidrug-resistant bacteria.
• Mechanism of Action Studies: Used in microbiological and biochemical research to study the inhibition of cell wall synthesis and bacterial lipid II binding.
• Preclinical & Clinical Research: Serves as an active pharmaceutical ingredient (API) in formulation studies for potential therapeutic applications against severe infections.
• Microbiology & Resistance Research: A critical tool for investigating bacterial resistance pathways and evaluating the efficacy of new antimicrobial agents.
• Biochemical Assay Development: Used as a standard or reference compound in high-throughput screening assays and target validation.
• Academic & Institutional Research: Fundamental research in medicinal chemistry, pharmacology, and infectious disease.

Basic Information

Product Name	Teixobactin
CAS No.	1613225-53-8
Molecular Formula	C₅₈H₉₅N₁₅O₁₅
Molecular Weight	1242.5 g/mol
Synonyms	Teixobactin; Antibiotic from Eleftheria terrae; TXA; Depsipeptide antibiotic; (2S)-2-[[(2S,5S,8S,11S,14S,17S,20S,23S,26S,29S,32S,35S,38S,41S)-11,14,17,20,23,26,29,32,35,38,41-Undecakis(1-methylethyl)-44-[(1S)-1-methylpropyl]-5,8-di(propan-2-yl)-2,4,7,10,13,16,19,22,25,28,31,34,37,40-tetradecaoxo-1-oxa-4,7,10,13,16,19,22,25,28,31,34,37,40-tridecazatetracyclo[40.3.1.1³,⁶.¹⁹,²²]octatetracontan-44-yl]amino]-3-phenylpropanoic acid
EINECS	Contact for details

Quality Control

Our Teixobactin is produced and tested under strict quality management systems to ensure the highest standards of purity and consistency for research use. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for research-grade active pharmaceutical ingredients (APIs), with specifications tailored to meet the rigorous demands of pharmaceutical R&D and preclinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.