Description

Atr Inhibitor 1 CAS NO 1613200-51-3 is a potent and selective small molecule inhibitor of the Ataxia Telangiectasia and Rad3-related (ATR) kinase, a critical component of the DNA damage response pathway. This compound is essential for advanced research in oncology and cellular biology, enabling the study of DNA repair mechanisms and cancer cell survival. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on developing novel cancer therapeutics and understanding genomic stability.

Application

• Oncology Research: Used as a key tool compound to investigate ATR kinase's role in DNA damage repair and its potential as a therapeutic target in various cancers.
• Drug Discovery & Development: Serves as a reference standard and a lead compound in high-throughput screening and preclinical studies for novel ATR inhibitors.
• Combination Therapy Studies: Employed in research exploring synergistic effects when combined with DNA-damaging agents, radiation, or other targeted therapies.
• Biochemical Assays: Utilized in vitro to characterize kinase inhibition potency, selectivity profiling, and mechanism-of-action studies.
• Cell Biology Research: Applied in cell-based models to study cell cycle checkpoint regulation, replication stress, and apoptosis.

Basic Information

Product Name	Atr Inhibitor 1
CAS No.	1613200-51-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	ATR Kinase Inhibitor 1; ATR Inhibitor; ATRi-1; Compound 1613200-51-3; (Research Code); DNA Damage Response Inhibitor; ATR Serine/Threonine Kinase Inhibitor
EINECS	Contact for details

Quality Control

Our Atr Inhibitor 1 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity confirmation and identity verification via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and strength is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.