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9-(3-Deoxy-3-Fluoro-β-D-Ribofuranosyl)-6-(5-Phenylpyridin-3-Yl)Purine CAS NO 1612191-96-4


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CAS No.:1612191-96-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

9-(3-Deoxy-3-Fluoro-β-D-Ribofuranosyl)-6-(5-Phenylpyridin-3-Yl)Purine is a high-purity nucleoside analog building block of significant interest in advanced pharmaceutical research and development. Its core value lies in its precise chemical structure, which is engineered for incorporation into novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. This compound is essential for medicinal chemists and research institutions focused on developing next-generation small molecule inhibitors and prodrugs targeting specific enzymatic pathways.

Application

  • Pharmaceutical Intermediate: Serves as a critical synthetic precursor for the development of novel nucleoside-based antiviral and anticancer agents.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of drug candidates.
  • Biochemical Tool Compound: Employed in enzymatic assays and target validation studies to investigate the mechanisms of nucleoside-metabolizing enzymes.
  • Prodrug Development: Acts as a key scaffold for designing prodrugs aimed at improving bioavailability and targeted delivery of active pharmaceutical ingredients (APIs).
  • Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs for custom synthesis and process development projects.
  • Academic Research: Utilized in university and institutional labs for fundamental research in chemical biology and drug design.

Basic Information

Product Name 9-(3-Deoxy-3-Fluoro-β-D-Ribofuranosyl)-6-(5-Phenylpyridin-3-Yl)Purine
CAS No. 1612191-96-4
Molecular Formula C21H18FN5O3
Molecular Weight 407.40 g/mol
Synonyms 6-(5-Phenylpyridin-3-yl)-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)purine; 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(5-phenyl-3-pyridinyl)-9H-purine; 1612191-96-4; Fluorinated nucleoside analog; 3'-Deoxy-3'-fluororibofuranosyl purine derivative; 6-(5-Phenyl-3-pyridinyl)purine riboside analog
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Quality Control

Our production of 9-(3-Deoxy-3-Fluoro-β-D-Ribofuranosyl)-6-(5-Phenylpyridin-3-Yl)Purine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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