Description

9-(3-Deoxy-3-Fluoro-β-D-Ribofuranosyl)-6-(Naphthalen-1-Yl)Purine is a high-purity nucleoside analog building block designed for advanced pharmaceutical research and development. This compound is critical for medicinal chemists exploring novel antiviral and anticancer therapeutics, particularly those targeting viral polymerases and cellular signaling pathways. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors for the synthesis of next-generation active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside analog antiviral and anticancer drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of therapeutic molecules.
• Biochemical Probes: Serves as a tool compound for studying enzyme kinetics and inhibition mechanisms, particularly for polymerases and kinases.
• Preclinical Development: Essential material for producing batches of candidate drugs for in vitro and in vivo efficacy and toxicity testing.
• Process Chemistry: Employed in route scouting and scale-up optimization for the commercial manufacturing of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	9-(3-Deoxy-3-Fluoro-β-D-Ribofuranosyl)-6-(Naphthalen-1-Yl)Purine
CAS No.	1612191-92-0
Molecular Formula	C₂₀H₁₇FN₄O₃
Molecular Weight	380.37 g/mol
Synonyms	6-(1-Naphthyl)-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)purine; 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(1-naphthyl)purine; 6-(Naphthalen-1-yl)-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purine; 1-Naphthalenepurine riboside derivative; Fluorinated nucleoside analog; 1612191-92-0
EINECS	Contact for details

Quality Control

Our 9-(3-Deoxy-3-Fluoro-β-D-Ribofuranosyl)-6-(Naphthalen-1-Yl)Purine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.