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6-(Furan-2-Yl)Purine-β-D-(3'-Deoxy-3'-Fluoro)Riboside CAS NO 1612191-89-5


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CAS No.:1612191-89-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-(Furan-2-Yl)Purine-β-D-(3'-Deoxy-3'-Fluoro)Riboside is a high-purity nucleoside analog designed for advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate in the creation of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and CROs engaged in medicinal chemistry and drug discovery programs. The product offers a critical building block for scientists exploring modified nucleosides with targeted biological activity.

Application

  • Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel nucleoside-based antiviral agents.
  • Anticancer Drug Research: Used in the development and screening of potential chemotherapeutic compounds targeting cellular proliferation.
  • Medicinal Chemistry: Acts as a specialized building block for structure-activity relationship (SAR) studies to optimize drug efficacy and selectivity.
  • Biochemical Research: Employed in enzymatic studies and as a probe to investigate nucleic acid metabolism and related biological pathways.
  • Pre-clinical Development: Supports the synthesis of candidate molecules for pharmacokinetic and toxicology evaluations.

Basic Information

Product Name 6-(Furan-2-Yl)Purine-β-D-(3'-Deoxy-3'-Fluoro)Riboside
CAS No. 1612191-89-5
Molecular Formula C14H13FN4O4
Molecular Weight 320.28 g/mol
Synonyms 6-(2-Furyl)purine-β-D-3'-deoxy-3'-fluororiboside; 3'-Deoxy-3'-fluoro-6-(2-furyl)-9-β-D-ribofuranosylpurine; 6-(2-Furanyl)-9-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]purine; 6-(Furan-2-yl)-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purine; 6-(2-Furyl)purine 3'-deoxy-3'-fluoro-β-D-riboside; 1612191-89-5; 6-(Furan-2-yl)purine β-D-3'-deoxy-3'-fluororiboside
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Quality Control

Our 6-(Furan-2-Yl)Purine-β-D-(3'-Deoxy-3'-Fluoro)Riboside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines
Heavy Metals < 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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