Description

6-Methylpurine-β-D-(3-Deoxy-3-Fluoro)Riboside is a chemically modified nucleoside analog, a key building block in medicinal chemistry and life science research. Its value lies in its structural features, which are designed to confer metabolic stability and specific biological activity, making it a crucial intermediate for developing novel therapeutic agents. This compound is primarily needed by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on antiviral, anticancer, and other nucleoside-based drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel nucleoside analog drugs, particularly for antiviral and anticancer applications.
• Antiviral Drug Research: Used in the development of modified nucleosides that target viral polymerases, with potential applications against a range of RNA and DNA viruses.
• Oncology Research: Investigated as a building block for prodrugs or active metabolites designed to inhibit cancer cell proliferation.
• Biochemical Tool Compound: Employed in enzymatic studies to understand substrate specificity and inhibition mechanisms of nucleoside-processing enzymes.
• Medicinal Chemistry SAR Studies: Utilized to explore structure-activity relationships (SAR) by modifying the purine base or sugar moiety to optimize drug-like properties.
• Labeled Compound Synthesis: Acts as a starting material for the synthesis of isotopically labeled (e.g., 13C, 15N, 3H) nucleosides for metabolic tracing and pharmacokinetic studies.

Basic Information

Product Name	6-Methylpurine-β-D-(3-Deoxy-3-Fluoro)Riboside
CAS No.	1612191-88-4
Molecular Formula	C11H14FN5O3
Molecular Weight	283.26 g/mol
Synonyms	6-Methylpurine-9-β-D-(3-Deoxy-3-fluoro)ribofuranoside; 3'-Deoxy-3'-fluoro-6-methylpurine riboside; 9-[(3-Deoxy-3-fluoro-β-D-ribofuranosyl)]-6-methylpurine; 6-Methyl-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)purine; 3'-Fluoro-3'-deoxy-6-methyladenosine analog; 6-MP-3'-F-riboside; 1612191-88-4; 6-Methylpurine 3'-fluoro-3'-deoxyriboside
EINECS	Contact for details

Quality Control

Our 6-Methylpurine-β-D-(3-Deoxy-3-Fluoro)Riboside is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all test results are provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.