Description

3'-Deoxy-3'-Fluoro-N6-Hydroxyadenosine is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate and a potential pharmacologically active agent, particularly in the exploration of antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in drug discovery, medicinal chemistry, and biochemical studies. The precise structural modifications offer unique properties for probing biological mechanisms and developing novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel nucleoside-based drug candidates.
• Antiviral Research: Investigated for its potential activity against a range of viral pathogens due to its modified sugar moiety.
• Oncology Drug Discovery: Used in research targeting cancer cell proliferation and exploring mechanisms of action for new chemotherapeutic agents.
• Biochemical Probe: Employed in enzymatic studies to understand substrate specificity and inhibition of nucleoside-processing enzymes.
• Medicinal Chemistry: A valuable compound for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Reference Standard: Used as an analytical standard in quality control and method development for related pharmaceutical products.

Basic Information

Product Name	3'-Deoxy-3'-Fluoro-N6-Hydroxyadenosine
CAS No.	1612191-87-3
Molecular Formula	C₁₀H₁₂FN₅O₄
Molecular Weight	285.23 g/mol
Synonyms	3'-Deoxy-3'-fluoroadenosine N6-hydroxide; 3'-Fluoro-3'-deoxy-N6-hydroxyadenosine; 6-Hydroxyamino-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)purine; 9-[(3-Deoxy-3-fluoro-β-D-ribofuranosyl)]-N6-hydroxyadenine; 3'-F-3'-d-N6-OH-Ado; Fludarabine N6-hydroxy analog; N6-Hydroxy-3'-deoxy-3'-fluoroadenosine; 1612191-87-3
EINECS	Contact for details

Quality Control

Our 3'-Deoxy-3'-Fluoro-N6-Hydroxyadenosine is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency suitable for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.