Description

(R)-4-(Dibenzylamino)-3-Fluoro-2-Methyl-2-Butanol is a chiral, fluorinated amino alcohol building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular architecture, which incorporates both a fluorine atom and a dibenzyl-protected amine group on a chiral butanol backbone, making it a versatile precursor for pharmaceutical and agrochemical intermediates. This compound is primarily needed by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for the synthesis of novel active ingredients, particularly those requiring stereochemical control and fluorination for enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel APIs, especially in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in transition metal catalysis.
• Agrochemical Research: Building block for creating new fluorinated pesticides and herbicides with improved efficacy and environmental profiles.
• Fluorine Chemistry Studies: Used in academic and industrial research to study the effects of fluorine introduction on molecular properties and reactivity.
• Peptidomimetic Synthesis: Incorporated into peptide analogs to modulate their conformation, stability, and biological activity.
• Material Science: Potential monomer or additive for specialty polymers where fluorine content imparts specific surface properties.

Basic Information

Product Name	(R)-4-(Dibenzylamino)-3-Fluoro-2-Methyl-2-Butanol
CAS No.	1609545-83-6
Molecular Formula	C19H24FNO
Molecular Weight	301.40 g/mol
Synonyms	(R)-3-Fluoro-2-methyl-4-(dibenzylamino)butan-2-ol; 4-(Dibenzylamino)-3-fluoro-2-methyl-2-butanol, (R)-; (R)-4-(Bis(phenylmethyl)amino)-3-fluoro-2-methyl-2-butanol; (2R)-4-(Dibenzylamino)-3-fluoro-2-methylbutan-2-ol; 1609545-83-6; Fluorinated Chiral Amino Alcohol; DBFMB (abbreviation)
EINECS	Contact for details

Quality Control

Our (R)-4-(Dibenzylamino)-3-Fluoro-2-Methyl-2-Butanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting R&D and process chemistry standards. Certificates of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), enantiomeric excess (typically ≥99% ee), and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its chemical nature, keep away from strong alkalis and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.