Description

(2E)-1-(2,5-Dimethoxyphenyl)-3-(3,4,5-Trimethoxyphenyl)Prop-2-En-1-One is a high-purity synthetic chalcone derivative characterized by its distinct methoxy-substituted aromatic structure. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for organic synthesis and medicinal chemistry research. It is primarily utilized by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential therapeutic agents targeting inflammation, cancer, and metabolic disorders.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis due to its chalcone backbone.
• Organic Synthesis Building Block: Used in cross-coupling reactions, cyclizations, and as a starting material for heterocyclic compounds.
• Agrochemical Research: Investigated for developing novel plant growth regulators or pesticides.
• Biochemical Probe: Utilized in biochemical assays to study enzyme inhibition or protein-ligand interactions.
• Material Science: Potential monomer or precursor for specialty polymers and organic electronic materials.

Basic Information

Product Name	(2E)-1-(2,5-Dimethoxyphenyl)-3-(3,4,5-Trimethoxyphenyl)Prop-2-En-1-One
CAS No.	1600502-76-8
Molecular Formula	C20H22O6
Molecular Weight	358.39 g/mol
Synonyms	(E)-1-(2,5-Dimethoxyphenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one; 2',5'-Dimethoxy-3,4,5-trimethoxychalcone; 3,4,5,2',5'-Pentamethoxychalcone; NSC 407296; Chalcone derivative 76-8; Pentamethoxychalcone; (E)-3,4,5,2',5'-Pentamethoxychalcone
EINECS	Contact for details

Quality Control

Our (2E)-1-(2,5-Dimethoxyphenyl)-3-(3,4,5-Trimethoxyphenyl)Prop-2-En-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment. We support compliance with cGMP, ISO, and other relevant quality standards for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.