Description

Deruxtecan is a potent and highly specific pharmaceutical compound belonging to the class of antibody-drug conjugates (ADCs). This compound matters as a critical payload component, enabling targeted delivery of cytotoxic agents directly to cancer cells, thereby maximizing therapeutic efficacy while minimizing systemic side effects. It is essential for pharmaceutical manufacturers and advanced research institutions engaged in the development of next-generation oncology therapeutics, particularly for solid tumors.

Application

• Primary Payload in Antibody-Drug Conjugates (ADCs): Serves as the cytotoxic warhead in targeted cancer therapies.
• Oncology Drug Development: Key intermediate for research and manufacturing of novel anti-cancer drugs.
• Bioconjugation Research: Used in studies to develop new linker-payload technologies for improved drug delivery.
• Preclinical and Clinical Studies: Essential material for pharmacological and toxicological evaluations in drug development pipelines.
• Pharmaceutical Reference Standard: Acts as a high-purity standard for quality control and analytical method development.

Basic Information

Product Name	Deruxtecan
CAS No.	1599440-13-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Datopotamab Deruxtecan; Dato-DXd; DS-1062a payload; DXd; Topoisomerase I inhibitor derivative; (3S,5R,15R,17S)-17-ethyl-17-hydroxy-11-methoxy-3-((2-((1-methyl-1H-1,2,3-triazol-4-yl)methoxy)ethyl)amino)-14,16-dioxa-2,4,12-triazatetracyclo[7.7.0.0³,⁷.0¹¹,¹⁵]hexadeca-1(9),4,6,10-tetraene-6,8,10-trione
EINECS	Contact for details

Quality Control

Our Deruxtecan is manufactured under strict quality management systems to ensure the highest standards of purity and consistency required for pharmaceutical development. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with stringent in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, inert environment. Due to its hygroscopic nature, the container must be sealed under an inert atmosphere (e.g., nitrogen or argon) and allowed to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.