Description

Afamelanotide Acetate is a synthetic, potent, and selective analog of α-melanocyte-stimulating hormone (α-MSH). This compound is a critical active pharmaceutical ingredient (API) valued for its specific pharmacological activity targeting the melanocortin-1 receptor (MC1R). It is primarily utilized in the pharmaceutical and advanced life science research sectors for the development of therapeutic agents and in-depth pharmacological studies.

Application

• Pharmaceutical API: Core active ingredient in the formulation of approved drug products.
• Photoprotection Therapy: Used in treatments for conditions like erythropoietic protoporphyria (EPP) to increase pain-free sun exposure.
• Preclinical & Clinical Research: Serves as a reference standard and investigational compound in dermatology and pigment disorder studies.
• Biochemical Research: Tool for studying melanocortin receptor signaling pathways and related physiological processes.
• Drug Development: Intermediate or target molecule in the synthesis and development of novel melanocortin-based therapeutics.

Basic Information

Product Name	Afamelanotide Acetate
CAS No.	1566590-77-9
Molecular Formula	C78H111N21O19 • (C2H4O2)x
Molecular Weight	~1648.9 (Free base)
Synonyms	Nle4-D-Phe7-α-MSH Acetate; Melanotan I Acetate; [Nle4, D-Phe7]-α-MSH Acetate; Afamelanotide; CUV1647; Scenesse (Brand Name); α-Melanocyte Stimulating Hormone Analog Acetate
EINECS	Contact for details

Quality Control

Our Afamelanotide Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, mass spectrometry for identity confirmation, and tests for residual solvents and related substances. A Certificate of Analysis (COA) detailing all specifications and results is provided to ensure traceability and compliance with cGMP guidelines for pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (IC)	5.0% - 12.0%
Bacterial Endotoxins	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.