Description

(3-Fluoro-4-(Methylsulfonyl)Phenyl)Methanol is a high-value fluorinated aromatic building block featuring both a hydroxymethyl and a methylsulfonyl functional group on a benzene ring. This unique bifunctional structure makes it a critical intermediate for the synthesis of advanced pharmaceutical compounds and agrochemicals, where it is used to modulate biological activity, solubility, and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the development of small molecule drugs, particularly kinase inhibitors and other targeted therapies where the fluorine and sulfone groups are pharmacologically relevant.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its structural motifs for enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or functionalized catalysts used in asymmetric synthesis and other specialized organic reactions.
• Material Science Research: Potential monomer or cross-linking agent in the synthesis of specialty polymers with specific electronic or surface properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring this precise fluorinated scaffold.

Basic Information

Product Name	(3-Fluoro-4-(Methylsulfonyl)Phenyl)Methanol
CAS No.	1564471-90-4
Molecular Formula	C8H9FO3S
Molecular Weight	204.22 g/mol
Synonyms	(3-Fluoro-4-methanesulfonylphenyl)methanol; (3-Fluoro-4-(methylsulfonyl)phenyl)methanol; 3-Fluoro-4-(methylsulfonyl)benzenemethanol; [3-Fluoro-4-(methylsulfonyl)phenyl]methanol; 4-(Hydroxymethyl)-2-fluoro-1-(methylsulfonyl)benzene; 2-Fluoro-4-(hydroxymethyl)-1-(methylsulfonyl)benzene; α-(3-Fluoro-4-(methylsulfonyl)phenyl)methanol
EINECS	Contact for details

Quality Control

Every batch of (3-Fluoro-4-(Methylsulfonyl)Phenyl)Methanol is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.