Description

n-(1,1-Dioxo-1Lambda6-Thiolan-3-Yl)-n-Methylcarbamoyl Chloride is a high-purity, reactive chemical intermediate belonging to the class of sulfonyl carbamoyl chlorides. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its reactive chlorocarbonyl and sulfone groups.
• Peptide Mimetics & PROTACs: Serves as a versatile linker or functional group introducer in the design of peptide mimetics and Proteolysis-Targeting Chimeras (PROTACs).
• Material Science Research: Employed in the development of specialty polymers and functional materials that require sulfone-based monomers.
• Chemical Biology Probes: Utilized to create activity-based probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	n-(1,1-Dioxo-1Lambda6-Thiolan-3-Yl)-n-Methylcarbamoyl Chloride
CAS No.	1536007-42-7
Molecular Formula	C7H10ClNO3S
Molecular Weight	223.68 g/mol
Synonyms	3-[(Methylcarbamoyl)chlorido]-1lambda6-thiolane-1,1-dione; N-Methyl-N-(1,1-dioxo-1lambda6-thiolan-3-yl)carbamoyl chloride; 1,1-Dioxo-1lambda6-thiolan-3-yl(methyl)carbamoyl chloride; Sulfolane-3-carboxamide, N-chloro-N-methyl-; Methyl(1,1-dioxothiolan-3-yl)carbamic chloride; Carbamic chloride, N-methyl-N-(1,1-dioxo-1lambda6-thiolan-3-yl)-
EINECS	Contact for details

Quality Control

Every batch of n-(1,1-Dioxo-1Lambda6-Thiolan-3-Yl)-n-Methylcarbamoyl Chloride is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency suitable for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.