Description

1-(2-Fluoroethyl)Azetidin-3-Ol is a high-value, fluorinated azetidine derivative, a key building block in modern pharmaceutical and agrochemical synthesis. Its unique structure, featuring both a fluorinated side chain and a hydroxylated azetidine ring, makes it a versatile intermediate for introducing specific pharmacophores and modulating physicochemical properties. This compound is essential for research and development chemists in the pharmaceutical industry, particularly for creating novel active ingredients in areas such as central nervous system (CNS) therapeutics and oncology.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially for CNS-targeting molecules and kinase inhibitors.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Chemical Biology Probe Synthesis: Serves as a building block for creating molecular probes to study enzyme function and biological pathways.
• Ligand Development for Catalysis: Employed in the preparation of specialized ligands for asymmetric synthesis and transition metal catalysis.
• Material Science Research: Investigated as a monomer or modifier for creating polymers with unique surface properties and stability.

Basic Information

Product Name	1-(2-Fluoroethyl)Azetidin-3-Ol
CAS No.	1500555-19-0
Molecular Formula	C5H10FNO
Molecular Weight	119.14 g/mol
Synonyms	3-Hydroxy-1-(2-fluoroethyl)azetidine; 1-(2-Fluoroethyl)-3-hydroxyazetidine; Azetidin-3-ol, 1-(2-fluoroethyl)-; 3-Azetidinol, 1-(2-fluoroethyl)-; 1-(2-Fluoroethyl)azetidin-3-ol; 1500555-19-0; 1-(2-Fluoroethyl)-3-azetidinol
EINECS	Contact for details

Quality Control

Our production of 1-(2-Fluoroethyl)Azetidin-3-Ol adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our facilities operate under cGMP principles where applicable, ensuring traceability and reliability for our global B2B clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.