Description

(S)-1-(5-Fluoro-2-Iodophenyl)Ethan-1-Ol is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its defined stereochemistry and the presence of both fluorine and iodine substituents, which are crucial for structure-activity relationship (SAR) studies and the development of targeted bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those focused on developing new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, especially in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the synthesis of advanced pesticides and herbicides, where the fluorine and iodine atoms contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers and advanced organic materials for electronic applications.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring high stereochemical purity and specific halogenated aryl motifs.

Basic Information

Item	Detail
Product Name	(S)-1-(5-Fluoro-2-Iodophenyl)Ethan-1-Ol
CAS No.	1454847-96-1
Molecular Formula	C8H8FIO
Molecular Weight	266.05 g/mol
Synonyms	(S)-1-(5-Fluoro-2-iodophenyl)ethanol; (S)-α-Methyl-5-fluoro-2-iodobenzyl alcohol; (1S)-1-(5-Fluoro-2-iodophenyl)ethan-1-ol; (S)-5-Fluoro-2-iodo-α-methylbenzyl alcohol; (S)-(-)-1-(5-Fluoro-2-iodophenyl)ethanol; 1454847-96-1; SCHEMBL21845427
EINECS	Contact for details

Quality Control

Every batch of (S)-1-(5-Fluoro-2-Iodophenyl)Ethan-1-Ol is produced and tested under strict quality management systems to ensure high chiral purity and chemical consistency. Our quality control protocols are designed to meet the stringent requirements of pharmaceutical R&D and cGMP guidelines where applicable. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, enantiomeric excess, and impurity profiles as determined by advanced analytical techniques including HPLC, GC, and chiral chromatography.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.