Description

(2-Bromo-4-Chloro-6-Fluorophenyl)Methanol is a versatile halogenated benzyl alcohol derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its multi-functional structure, which provides reactive sites for constructing complex molecules with high precision. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting CNS disorders and infectious diseases.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core.
• Liquid Crystal & OLED Material Research: Used in the creation of fluorinated organic compounds for electronic display and lighting applications.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Ligand & Catalyst Development: Useful for synthesizing specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Intermediate for introducing halogenated phenyl groups into polymer chains to alter physical properties like flame retardancy and stability.

Basic Information

Product Name	(2-Bromo-4-Chloro-6-Fluorophenyl)Methanol
CAS No.	1449008-26-7
Molecular Formula	C7H5BrClFO
Molecular Weight	239.47 g/mol
Synonyms	2-Bromo-4-chloro-6-fluorobenzyl alcohol; (2-Bromo-4-chloro-6-fluorophenyl)methanol; 1-(Bromochlorofluoromethyl)benzene-3-ol; α-Bromo-α-chloro-α-fluoro-o-cresol; Benzenemethanol, 2-bromo-4-chloro-6-fluoro-; Halogenated Benzyl Alcohol Derivative; BCFP-Methanol
EINECS	Contact for details

Quality Control

Our (2-Bromo-4-Chloro-6-Fluorophenyl)Methanol is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.