Description

(6-Bromo-2-Fluoro-3-Iodophenyl)Methanol is a high-purity, multi-halogenated benzyl alcohol derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile, functionalized aromatic scaffold for constructing complex molecules, particularly in pharmaceutical discovery and materials science. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise building blocks for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers where halogen atoms tune electronic properties and molecular interactions.
• Chemical Biology Probes: Utilized as a core structure for synthesizing molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	(6-Bromo-2-Fluoro-3-Iodophenyl)Methanol
CAS No.	1449008-03-0
Molecular Formula	C7H5BrFIO
Molecular Weight	345.92 g/mol
Synonyms	2-Fluoro-6-bromo-3-iodobenzyl alcohol; (6-Bromo-2-fluoro-3-iodophenyl)methanol; 1-(Bromomethyl)-2-fluoro-3-iodo-5-bromobenzene (tautomer); 3-Iodo-2-fluoro-6-bromobenzyl alcohol; 6-Bromo-2-fluoro-3-iodo-benzenemethanol; Benzenemethanol, 6-bromo-2-fluoro-3-iodo-
EINECS	Contact for details

Quality Control

Every batch of (6-Bromo-2-Fluoro-3-Iodophenyl)Methanol is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (by HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and oxidation, prolonged exposure to air or light should be avoided. Keep the container tightly sealed when not in use to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.