Description

5-Iodouridine-5'-o-Diphosphate Trisodium Salt is a modified nucleotide diphosphate analog of significant biochemical and pharmacological interest. This compound serves as a critical building block and research tool in the study of nucleic acid metabolism, enzyme mechanisms, and antiviral drug development. It is essential for researchers and manufacturers in the fields of pharmaceutical development, molecular biology, and biochemical research, particularly for those investigating nucleoside-based therapies and metabolic pathways.

Application

• Biochemical Research: As a substrate or inhibitor for studies involving RNA polymerases, kinases, and other nucleotide-processing enzymes.
• Antiviral Drug Development: Serves as a key intermediate or precursor in the synthesis of novel nucleoside analog prodrugs targeting viral replication.
• Enzymology Studies: Used to probe the active sites and catalytic mechanisms of enzymes that utilize uridine derivatives.
• Metabolic Pathway Analysis: A tool for tracing and understanding nucleotide salvage and synthesis pathways in cellular systems.
• Labeled Compound Synthesis: Potential precursor for the preparation of radiolabeled (e.g., with I-125) nucleotides for diagnostic or tracking applications.
• Academic & Industrial R&D: Fundamental research reagent in universities, contract research organizations (CROs), and biotech companies.

Basic Information

Product Name	5-Iodouridine-5'-o-Diphosphate Trisodium Salt
CAS No.	1448858-83-0
Molecular Formula	C9H11IN2Na3O14P2
Molecular Weight	Contact for details
Synonyms	5-Iodo-UDP trisodium salt; 5-Iodouridine 5'-diphosphate trisodium salt; UDP-5-I trisodium; 5-I-UDP Na3; 5-Iodouridine diphosphate sodium salt; 2',3',5'-Tri-O-acetyl-5-iodouridine; 5-Iodo-2',3',5'-tri-O-acetyluridine (related precursor)
EINECS	Contact for details

Quality Control

Our 5-Iodouridine-5'-o-Diphosphate Trisodium Salt is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support research and development with materials suitable for GMP-grade synthesis upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.