Description

Futibatinib CAS NO 1448169-71-8 is a potent and selective small-molecule inhibitor of fibroblast growth factor receptor (FGFR), specifically designed to target dysregulated signaling pathways in cancer. This compound matters for its role in advanced oncology research and targeted therapy development, offering a mechanism to address tumors with FGFR genetic alterations. It is primarily needed by pharmaceutical R&D teams, clinical research organizations (CROs), and manufacturers of active pharmaceutical ingredients (APIs) focused on precision medicine for solid tumors.

Application

• Research and development of targeted cancer therapies, particularly for cholangiocarcinoma and other solid tumors.
• Active Pharmaceutical Ingredient (API) in the manufacture of investigational and approved oncology drugs.
• Preclinical and clinical studies investigating the efficacy of FGFR inhibition.
• Biochemical research for studying FGFR signaling pathways and mechanisms of resistance.
• Reference standard for analytical method development and quality control in pharmaceutical production.
• Formulation development for oral dosage forms in oncology.

Basic Information

Product Name	Futibatinib
CAS No.	1448169-71-8
Molecular Formula	C26H27N5O5
Molecular Weight	489.52 g/mol
Synonyms	TAS-120; LY-3076226; Futibatinib (TAS-120); 6-[(3,5-Dimethoxyphenyl)amino]-N-(2,3-dihydro-1H-inden-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide; FGFR Inhibitor TAS-120; 6-[(3,5-Dimethoxyphenyl)amino]-N-(2,3-dihydro-1H-inden-4-yl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide
EINECS	Contact for details

Quality Control

Our Futibatinib is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.