Description

(2,4-Difluoro-3-(Trifluoromethyl)Phenyl)Methanol is a high-value fluorinated aromatic building block, distinguished by its unique substitution pattern. This compound is critical for introducing specific steric and electronic properties into advanced molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, where its fluorine atoms are leveraged to modulate bioavailability, metabolic stability, and binding affinity.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in areas like kinase inhibitors, antiviral agents, and CNS-targeted therapies.
• Agrochemical Active Ingredient Synthesis: Used in the research and production of next-generation herbicides and fungicides, where the difluoro and trifluoromethyl groups enhance lipophilicity and biological activity.
• Liquid Crystal & OLED Material Research: Serves as a precursor in the synthesis of fluorinated components for electronic display and lighting technologies.
• Advanced Polymer Modification: Employed to create specialty monomers that impart unique chemical resistance and thermal stability to high-performance polymers.
• Cross-Coupling Reactions: The benzylic alcohol can be functionalized or the aromatic ring can participate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed couplings to construct complex molecules.

Basic Information

Product Name	(2,4-Difluoro-3-(Trifluoromethyl)Phenyl)Methanol
CAS No.	1445995-77-6
Molecular Formula	C8H5F5O
Molecular Weight	212.12 g/mol
Synonyms	[2,4-Difluoro-3-(trifluoromethyl)phenyl]methanol; 2,4-Difluoro-3-(trifluoromethyl)benzyl Alcohol; 3-(Trifluoromethyl)-2,4-difluorobenzyl Alcohol; α,α,α,2,4-Pentafluorotoluene; (3-Trifluoromethyl-2,4-difluorophenyl)methanol; 2,4-Difluoro-α,α,α-trifluorotoluene; Pentafluorobenzyl Alcohol Derivative
EINECS	Contact for details

Quality Control

Our (2,4-Difluoro-3-(Trifluoromethyl)Phenyl)Methanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 99.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.