Description

4-Chloro-3-Fluoro-5-(Trifluoromethyl)Benzylalcohol is a high-value, multi-functional aromatic building block characterized by its unique halogenated and trifluoromethylated structure. This compound is essential for the synthesis of advanced agrochemicals and pharmaceuticals, where its scaffold provides critical bioactivity and metabolic stability. It is primarily sought after by research and development chemists, process development teams, and manufacturers in the fine chemical, agrochemical, and pharmaceutical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a critical building block for novel herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced lipophilicity and target binding.
• Liquid Crystal Materials: Used in the development of advanced liquid crystal compounds for display technologies due to its polarizable aromatic core and halogen substituents.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to construct complex polyfunctional aromatic systems for material science.
• Fluorinated Polymer Research: Acts as a monomer or modifier in the research and development of specialty fluorinated polymers with unique surface properties and chemical resistance.

Basic Information

Product Name	4-Chloro-3-Fluoro-5-(Trifluoromethyl)Benzylalcohol
CAS No.	1431329-65-5
Molecular Formula	C8H5ClF4O
Molecular Weight	228.57 g/mol
Synonyms	(4-Chloro-3-fluoro-5-(trifluoromethyl)phenyl)methanol; 1-(Chloro-3-fluoro-5-(trifluoromethyl)phenyl)methanol; 4-Chloro-3-fluoro-α-(trifluoromethyl)benzyl alcohol; 4-Chloro-3-fluoro-5-trifluoromethylbenzyl alcohol; 4-Chloro-3-fluoro-5-(trifluoromethyl)benzenemethanol; 4-Chloro-3-fluoro-5-(trifluoromethyl)phenylmethanol; CAS 1431329-65-5
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-3-Fluoro-5-(Trifluoromethyl)Benzylalcohol adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity. Every lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support customer audits and regulatory documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.