Description

1-(2-((4-Fluorophenyl)Ethynyl)Phenyl)Ethanone is a specialized organic building block featuring a fluorinated aromatic ethynyl ketone structure. This compound is valued for its role as a key intermediate in advanced organic synthesis, particularly in the development of pharmaceuticals and functional materials. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or cancer.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of advanced polymers, liquid crystals, or organic electronic materials.
• Chemical Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Sonogashira, Suzuki) to introduce conjugated ethynyl-aryl systems.
• Fluorine Chemistry Studies: Used as a model compound in research exploring the effects of fluorination on molecular properties and reactivity.

Basic Information

Product Name	1-(2-((4-Fluorophenyl)Ethynyl)Phenyl)Ethanone
CAS No.	1426258-82-3
Molecular Formula	C16H11FO
Molecular Weight	238.26 g/mol
Synonyms	2-[(4-Fluorophenyl)ethynyl]acetophenone; 1-[2-[(4-Fluorophenyl)ethynyl]phenyl]ethanone; 2-(4-Fluorophenylethynyl)acetophenone; 1-Acetyl-2-[(4-fluorophenyl)ethynyl]benzene; 2-Acetylbiphenyl-4-fluoro derivative (ethynyl-linked); 4-Fluoro-α,α'-diaryl acetylene ketone
EINECS	Contact for details

Quality Control

Our production of 1-(2-((4-Fluorophenyl)Ethynyl)Phenyl)Ethanone adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.