Description

Mefatinib CAS NO 1417695-74-9 is a potent and selective small molecule inhibitor targeting specific tyrosine kinases involved in critical cellular signaling pathways. This compound is of significant value for pharmaceutical research and development, particularly in the field of oncology. It is primarily needed by research institutions, biotechnology companies, and pharmaceutical manufacturers engaged in the discovery and development of novel targeted cancer therapies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced investigational drug candidates.
• Biochemical Research: Used as a selective tool compound in vitro and in vivo to study specific kinase signaling pathways and their role in disease progression.
• Oncology R&D: A critical material for preclinical studies aimed at evaluating the efficacy and mechanism of action of targeted anti-cancer agents.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Drug Discovery Programs: Integral to high-throughput screening and structure-activity relationship (SAR) studies for identifying new therapeutic leads.

Basic Information

Product Name	Mefatinib
CAS No.	1417695-74-9
Molecular Formula	C₂₄H₂₅FN₆O₂
Molecular Weight	448.49 g/mol
Synonyms	Mefatinib; 1417695-74-9; N-[3-Fluoro-4-[[6-(4-methyl-1-piperazinyl)-2-pyridinyl]oxy]phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide; TAK-659; SNS-062; UNII-9J97361Y2I
EINECS	Contact for details

Quality Control

Our Mefatinib is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-grade standards suitable for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.