Description

1H-Benzimidazol-5-Yl Trifluoromethyl Sulphone is a high-purity, advanced pharmaceutical intermediate characterized by its benzimidazole core and trifluoromethylsulfone functional group. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting kinase inhibition or other enzyme-related pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic agents.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel pesticides and herbicides with enhanced efficacy.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological processes and target validation.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce the benzimidazole-trifluoromethylsulfone moiety into complex molecules.

Basic Information

Product Name	1H-Benzimidazol-5-Yl Trifluoromethyl Sulphone
CAS No.	1417341-55-9
Molecular Formula	C8H5F3N2O2S
Molecular Weight	250.20 g/mol
Synonyms	5-(Trifluoromethylsulfonyl)-1H-benzimidazole; 1H-Benzimidazole-5-sulfonic acid, trifluoromethyl-; 5-(Trifluoromethanesulfonyl)-1H-benzimidazole; Benzimidazol-5-yl trifluoromethyl sulfone; Trifluoromethyl 1H-benzimidazol-5-yl sulphone; 1417341-55-9; 5-Trifluoromethylsulfonylbenzimidazole
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazol-5-Yl Trifluoromethyl Sulphone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.