Description

Evobrutinib is a highly selective, irreversible Bruton's tyrosine kinase (BTK) inhibitor, a key therapeutic agent in the development of treatments for autoimmune diseases. Its primary value lies in its targeted mechanism of action, which modulates B-cell receptor signaling pathways implicated in conditions like multiple sclerosis. This product is essential for pharmaceutical R&D teams, clinical research organizations, and manufacturers developing novel immunomodulatory therapies. We supply high-purity Evobrutinib CAS NO 1415823-73-2 to support critical drug discovery and development programs globally.

Application

• Pharmaceutical Active Pharmaceutical Ingredient (API): Core component in the formulation of investigational and commercial autoimmune disease therapeutics.
• Preclinical & Clinical Research: Used in vitro and in vivo studies to investigate BTK inhibition efficacy, pharmacokinetics, and safety profiles.
• Reference Standard: Serves as a high-purity analytical standard for quality control, method development, and regulatory submissions.
• Drug Discovery & Development: A key building block for medicinal chemistry programs aiming to develop next-generation BTK inhibitors.
• Biochemical Assay Development: Utilized in high-throughput screening and enzymatic assays to study B-cell signaling pathways.

Basic Information

Product Name	Evobrutinib
CAS No.	1415823-73-2
Molecular Formula	C₂₅H₂₈N₆O₂
Molecular Weight	444.53 g/mol
Synonyms	M2951; (S)-N-(3-(6-(4-(1,4-Dimethyl-3-oxopiperazin-2-yl)phenylamino)-4-methyl-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidin-2-yl)phenyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxamide; (S)-Evobrutinib; M-2951; BRN 2788; EVO-001
EINECS	Contact for details

Quality Control

Our Evobrutinib is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent determination, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided and can be tailored to support regulatory filings under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, 15-25°C. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.