Description

2,6-Diaminopurine -9-β-D-(2',3',5'-Tri-o-Benzoyl-2'-C-Methyl) Riboside is a sophisticated nucleoside analog and a key advanced intermediate in pharmaceutical research and development. This compound matters for its critical role as a building block in the synthesis of novel antiviral and anticancer agents, particularly modified nucleoside therapeutics. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries focused on nucleoside-based drug discovery.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel nucleoside analogs for antiviral and anticancer drug candidates.
• Antiviral Research: Used in the development of potential therapeutics targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a building block for creating purine-based compounds that may act as kinase inhibitors or antimetabolites.
• Biochemical Tool: Employed in enzymatic studies and as a substrate analog to investigate nucleoside metabolism and related pathways.
• Process Chemistry: Utilized in scaling up and optimizing synthetic routes for the production of active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for the preparation of labeled compounds (e.g., deuterated, C13) for pharmacokinetic and metabolic studies.

Basic Information

Product Name	2,6-Diaminopurine -9-β-D-(2',3',5'-Tri-o-Benzoyl-2'-C-Methyl) Riboside
CAS No.	1412427-05-4
Molecular Formula	C33H30N6O7
Molecular Weight	610.63 g/mol
Synonyms	9-[(2R,3R,4R,5R)-3,4-Bis(benzoyloxy)-5-[(benzoyloxy)methyl]-3-methyloxolan-2-yl]-2,6-diaminopurine; 2,6-Diamino-9-[(2'R,3'R,4'R,5'R)-3',4'-bis(benzoyloxy)-5'-[(benzoyloxy)methyl]-3'-methyloxolan-2'-yl]purine; 2',3',5'-Tri-O-benzoyl-2'-C-methyl-2,6-diaminopurine riboside; 2'-C-Methyl-2,6-diaminopurine riboside tri-benzoate; DAP Riboside Tri-benzoate Derivative; Advanced Nucleoside Intermediate 1412427-05-4
EINECS	Contact for details

Quality Control

Our 2,6-Diaminopurine -9-β-D-(2',3',5'-Tri-o-Benzoyl-2'-C-Methyl) Riboside is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.