Description

2-Amino-2-(4-Fluoro-3-(Trifluoromethyl)Phenyl)Ethanol Hydrochloride is a high-value pharmaceutical intermediate and fine chemical building block. Its molecular structure, featuring both amino and fluoro/trifluoromethyl substituents, makes it a critical precursor for the synthesis of advanced active pharmaceutical ingredients (APIs). This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine-containing moiety for enhanced bioactivity and stability.
• Chemical Research & Development: Serves as a versatile chiral synthon in medicinal chemistry for structure-activity relationship (SAR) studies.
• Ligand & Catalyst Preparation: Potential precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorinated Compound Libraries: Essential component for combinatorial chemistry in generating libraries of fluorinated compounds for high-throughput screening.

Basic Information

Product Name	2-Amino-2-(4-Fluoro-3-(Trifluoromethyl)Phenyl)Ethanol Hydrochloride
CAS No.	1394820-12-2
Molecular Formula	C9H8F4NO•HCl
Molecular Weight	261.62 g/mol (Free base)
Synonyms	2-Amino-2-(4-Fluoro-3-(trifluoromethyl)phenyl)ethan-1-ol hydrochloride; 1-(4-Fluoro-3-(trifluoromethyl)phenyl)-2-aminoethanol hydrochloride; 2-Amino-1-(4-fluoro-3-(trifluoromethyl)phenyl)ethanol HCl; 4-Fluoro-α-(aminomethyl)-3-(trifluoromethyl)benzenemethanol hydrochloride; 1394820-12-2; (R/S)-2-Amino-2-(4-fluoro-3-(trifluoromethyl)phenyl)ethanol hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-2-(4-Fluoro-3-(Trifluoromethyl)Phenyl)Ethanol Hydrochloride is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for research and GMP-grade synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles by HPLC are available for every batch upon request, ensuring full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.