Description

2-Amino-5-(Trifluoromethoxy)Phenyl Thiocyanate is a specialized aromatic compound featuring both amino and thiocyanate functional groups on a trifluoromethoxy-substituted benzene ring. This unique structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex molecules. It is primarily sought after by R&D chemists and process development teams in the agrochemical and pharmaceutical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the trifluoromethoxy and thiocyanate groups contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers and functional materials with specific electronic or surface properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes to study enzyme activity or biological pathways due to its reactive functional groups.

Basic Information

Product Name	2-Amino-5-(Trifluoromethoxy)Phenyl Thiocyanate
CAS No.	1391054-04-8
Molecular Formula	C8H5F3N2OS
Molecular Weight	234.20 g/mol
Synonyms	2-Amino-5-(trifluoromethoxy)benzenethiocyanate; 1-Amino-4-(trifluoromethoxy)-2-thiocyanatobenzene; 2-Thiocyanato-5-(trifluoromethoxy)aniline; 5-(Trifluoromethoxy)-2-aminophenyl thiocyanate; Benzenethiocyanate, 2-amino-5-(trifluoromethoxy)-; [2-Amino-5-(trifluoromethoxy)phenyl] thiocyanate
EINECS	Contact for details

Quality Control

Our 2-Amino-5-(Trifluoromethoxy)Phenyl Thiocyanate is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.