Description

Vodobatinib is a potent and selective small molecule inhibitor with significant therapeutic potential. Its primary value lies in its targeted mechanism of action, which makes it a critical compound for advanced pharmaceutical research and development. This product is essential for researchers and manufacturers in the global pharmaceutical and biotechnology sectors, particularly those focused on developing novel oncology treatments. Vodobatinib CAS NO 1388803-90-4 represents a high-purity reference standard for drug discovery and analytical applications.

Application

• Pharmaceutical R&D: Serves as a key active pharmaceutical ingredient (API) intermediate or reference standard in the development of targeted cancer therapies.
• Kinase Inhibition Studies: Used in biochemical and cellular assays to study specific kinase pathways and their role in disease progression.
• Preclinical Research: Employed in in vitro and in vivo studies to evaluate efficacy, pharmacokinetics, and toxicology profiles.
• Analytical Standard: Functions as a high-purity certified reference material (CRM) for quality control and method validation in analytical laboratories (HPLC, LC-MS).
• Process Chemistry: Utilized as a building block or intermediate in the scalable synthesis of complex drug molecules.

Basic Information

Product Name	Vodobatinib
CAS No.	1388803-90-4
Molecular Formula	C₂₉H₃₀N₈O₂
Molecular Weight	522.61 g/mol
Synonyms	Vodobatinib; PF-06747775; 6-[6-(1-Methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]quinoline; PF06747775; UNII-1VGE2V865Y; 1VGE2V865Y; (6-(6-(1-Methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)quinoline)
EINECS	Contact for details

Quality Control

Our Vodobatinib is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development purposes. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS). A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.