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Sodium(R)-2-(5-(2-(3-Ethylureido)-6-Fluoro-7-(Tetrahydrofuran-2-Yl)-1H-Benzo[D]Imidazol-5-Yl)Pyrimidin-2-Yl)Propan-2-Ylphosphate CAS NO 1384984-31-9
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CAS No.:1384984-31-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Sodium(R)-2-(5-(2-(3-Ethylureido)-6-Fluoro-7-(Tetrahydrofuran-2-Yl)-1H-Benzo[D]Imidazol-5-Yl)Pyrimidin-2-Yl)Propan-2-Ylphosphate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of targeted therapeutic agents, particularly in oncology and antiviral drug discovery pipelines. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs).
Application
- Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates, especially kinase inhibitors.
- Oncology Research: Used in the development of targeted cancer therapies due to its specific molecular scaffold.
- Antiviral Drug Development: Serves as a precursor in the research of antiviral compounds.
- Biochemical Research: Utilized as a reference standard or probe in biochemical and pharmacological studies to understand enzyme interactions.
- Preclinical Development: Supplied for use in formulation studies and preclinical testing of new chemical entities (NCEs).
- Custom Synthesis: Starting material for contract manufacturing organizations (CMOs) specializing in complex, multi-step organic synthesis.
Basic Information
| Product Name | Sodium(R)-2-(5-(2-(3-Ethylureido)-6-Fluoro-7-(Tetrahydrofuran-2-Yl)-1H-Benzo[D]Imidazol-5-Yl)Pyrimidin-2-Yl)Propan-2-Ylphosphate |
| CAS No. | 1384984-31-9 |
| Molecular Formula | C25H30FN6NaO6P |
| Molecular Weight | 598.51 g/mol |
| Synonyms | Sodium (R)-2-[5-[2-(3-Ethylureido)-6-fluoro-7-(oxolan-2-yl)-1H-benzimidazol-5-yl]pyrimidin-2-yl]propan-2-yl phosphate; (R)-2-(5-(2-(3-Ethylureido)-6-Fluoro-7-(Tetrahydrofuran-2-yl)-1H-Benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl Phosphate Sodium Salt; 1384984-31-9; UNII-6V8G8P8V4S; 6V8G8P8V4S; Sodium 2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1H-benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl hydrogen phosphate |
| EINECS | Contact for details |
Quality Control
Our Sodium(R)-2-(5-(2-(3-Ethylureido)-6-Fluoro-7-(Tetrahydrofuran-2-Yl)-1H-Benzo[D]Imidazol-5-Yl)Pyrimidin-2-Yl)Propan-2-Ylphosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity and identity confirmation, residual solvent analysis, and chiral purity verification to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccated environment after opening to maintain stability and prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms to reference standard |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Chiral Purity (Chiral HPLC) | ≥ 99.0% ee |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH Q3C guidelines |
| Heavy Metals | < 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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